| Titre : | DEVELOPMENT OF GENOMICS TYPING WEBTOOL OF HELICOBACTER PYLORI | | Type de document : | thèse | | Auteurs : | EL KAMILI FADOUA, Auteur | | Année de publication : | 2022 | | Langues : | Anglais (eng) | | Mots-clés : | Helicobacter pylori website Drug resistance genomic Analysis Hélicobactere pylori Site Résistance aux antibiotics Analyse génomique هيليكوباكتر بيلوري موقع مقاومة المضادات الحيوية التحليل الجينومي | | Résumé : | Helicobacter pylori is present in all regions of the world with a higher prevalence in developing countries. Almost half of the world’s population are infected with this bacterium. In this study, we present the first webtool for H pylori resistance, typing and virulence prediction based on the detection of SNPs and genes from WGS data of H pylori. The new webserver of H.pylori was made to make typing an easy approach by performing a detailed analysis of genetic variants of H.pylori strains, to provide information on genetic diversity and transmission of the bacteria in the whole world. The webserver also provides tools for virulence and resistance analysis which can play an important role in orienting the therapeutic approach and offer rapid identification and diagnosis for disease control and prevention. | | Numéro (Thèse ou Mémoire) : | MM0232022 | | Président : | Ibrahimi Azeddine | | Directeur : | EL Allali Achraf | | Juge : | Laamarti Mariem | | Juge : | Kandoussi Ilham |
DEVELOPMENT OF GENOMICS TYPING WEBTOOL OF HELICOBACTER PYLORI [thèse] / EL KAMILI FADOUA, Auteur . - 2022. Langues : Anglais ( eng) | Mots-clés : | Helicobacter pylori website Drug resistance genomic Analysis Hélicobactere pylori Site Résistance aux antibiotics Analyse génomique هيليكوباكتر بيلوري موقع مقاومة المضادات الحيوية التحليل الجينومي | | Résumé : | Helicobacter pylori is present in all regions of the world with a higher prevalence in developing countries. Almost half of the world’s population are infected with this bacterium. In this study, we present the first webtool for H pylori resistance, typing and virulence prediction based on the detection of SNPs and genes from WGS data of H pylori. The new webserver of H.pylori was made to make typing an easy approach by performing a detailed analysis of genetic variants of H.pylori strains, to provide information on genetic diversity and transmission of the bacteria in the whole world. The webserver also provides tools for virulence and resistance analysis which can play an important role in orienting the therapeutic approach and offer rapid identification and diagnosis for disease control and prevention. | | Numéro (Thèse ou Mémoire) : | MM0232022 | | Président : | Ibrahimi Azeddine | | Directeur : | EL Allali Achraf | | Juge : | Laamarti Mariem | | Juge : | Kandoussi Ilham |
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